Demodex Solutions story
More Than Two Decades of Innovation in Demodex Skin Care
Our Story
More than two decades ago, our journey began with a simple question:
Why were so many people struggling with persistent skin problems despite trying countless conventional treatments?
At the time, awareness of the role that Demodex mites could play in skin health was extremely limited. While many people were living with persistent redness, acne-like breakouts, irritation, and sensitive skin, few solutions addressed the underlying factors that could contribute to these ongoing concerns.
During our search for better answers, we discovered the original Zhongzhou Zinc Oxide & Sublimed Sulfur Ointment—a traditional formulation that had already earned a strong reputation for helping skin affected by Demodex-related imbalances.
The results we observed were remarkable. It became clear that this formulation offered something different from the products commonly available at the time. Rather than simply masking visible symptoms, it supported the skin in restoring a healthier state of balance.
Bringing Zhongzhou to the World
Recognizing its potential, we began introducing the original Zhongzhou ointment to customers around the world. As more people discovered the product, thousands shared positive experiences and stories of renewed confidence.
These real-world results confirmed that many individuals had long been searching for an alternative approach to caring for skin affected by persistent redness, blemishes, and other Demodex-related concerns.
A New Generation: The Development of ZZ Cream
Although the original Zhongzhou ointment proved highly effective, there was room for refinement.
Working closely with the original manufacturer, a cosmetic version of the formulation was developed: ZZ Cream.
The goal was not to replace the original formula, but to create a product that was more suitable for long-term cosmetic use while preserving the principles that had made the original ointment so respected.
The result was a carefully refined formulation with an improved cosmetic texture and skin feel, designed to fit comfortably into a daily skincare routine while continuing to support skin affected by Demodex-related imbalance.
Since its introduction, ZZ Cream has become our flagship product and remains one of the most trusted non-prescription skincare solutions for individuals seeking healthier-looking, more balanced skin.
Continuous Refinement
Innovation did not stop with ZZ Cream.
Over the years, we continued expanding our range with complementary skincare products designed to support different aspects of the skin and scalp.
Our collection now includes gentle cleansers, moisturizers, shampoos, and specialized skincare products developed to work together as part of a complete skin-support routine.
Each new product has been created with the same philosophy that has guided us from the very beginning:
- Support the skin's natural balance.
- Respect the skin barrier.
- Prioritize long-term skin health over temporary cosmetic fixes.
- Continuously refine formulations based on decades of experience and customer feedback.
Pioneering Demodex Awareness Since 2003
Since 2003, we have dedicated ourselves not only to providing specialized skincare, but also to raising awareness of the relationship between Demodex mites and persistent skin concerns.
Long before the subject became widely discussed, we were helping customers understand the importance of maintaining a balanced skin ecosystem.
Today, our products are trusted by customers in more than 100 countries, and our mission remains unchanged:
To provide high-quality, non-prescription skincare that helps people regain confidence through healthier-looking, more balanced skin.
More than twenty years later, we continue to build on the same foundation that started it all—with the discovery of the original Zhongzhou ointment and the development of the cosmetic formulation now known around the world as ZZ Cream.

